CIFASD (Collaborative Initiative on Fetal Alcohol Spectrum Disorders) is a multisite consortium supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The purpose of this consortium is to inform and develop effective interventions and treatment approaches for Fetal Alcohol Spectrum Disorders (FASD), through multidisciplinary research involving basic, behavioral, and clinical investigators and projects. We hope to develop an infrastructure to foster collaboration and coordinate basic, clinical, and translational research on FASD., Data were collected across multiple grant cycles spanning 2003 – present. For data from 2003-2022 (Phases 1-4), please go to https://cifasd.org/data-sharing/ to request these CIFASD data. Data from 2022 (Phase 5) and beyond are deposited into the NIAAA Data Archive ( https://www.niaaa.nih.gov/research/niaaa-data-archive). , CIFASD investigators designed and implemented the study and/or provided data but did not necessarily participate in the analysis or writing of this report. A list of CIFASD investigators and projects can be found at https://cifasd.org/research/ . , and CIFASD has received support from NIAAA under award numbers: U01AA014786, U01AA014790, U01AA014809, U01AA014812, U01AA014829, U01AA014834, U01AA014835, U01AA017120, U01AA017122, U01AA017123, U01AA017124, U01AA021651, U01AA026101, U01AA026102, U01AA026103, U01AA026104, U01AA026108, U01AA030164, U01AA030185, U01AA030187, U24AA014811, U24AA014815, U24AA014818, U24AA014828, U24AA014830, U24AA030169, UH2AA026106, UH2AA026109, UH2AA029050, UH2AA029056, UH2AA029062, and UH2AA030186.
This dataset was generated from experiments using purified materials. Experiments were designed to study phase separation of SARS-CoV-2 Nucleocapsid protein.
This data is from the fossil assemblage excavated by the Olduvai Landscape Paleoanthropology Project from 2010 - 2014 at the Douglas Korongo site in Olduvai Gorge, Tanzania.
Citation to related publication:
Title:
Dataset 1. Skeletal part profiles for OLAPP DK trenchs
Spectroscopy data were collected on a BioTek Synergy H1 plate reader, then exported to and analyzed in Excel. 3D charts used in the manuscript were generated with OriginPro. Microscopy images are in proprietary .nd2 format of Nikon Elements software. .nd2 files were opened and processed with ImageJ. Gels were imaged on a BioRad Chemidoc.
Laughlin, P. M.; Young, K.; Gonzalez-Guiterrez, G.; Wang, J. C.-Y.,; Zlotnick, A. A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation. 2024.
Title:
Raw data for "A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation"
Spectroscopy data were collected on a BioTek Synergy H1 plate reader, then exported to and analyzed in Excel. 3D charts used in the manuscript were generated with OriginPro. Microscopy images are in proprietary .nd2 format of Nikon Elements software. .nd2 files were opened and processed with ImageJ. Gels were imaged on a BioRad Chemidoc.
Laughlin, P. M.; Young, K.; Gonzalez-Guiterrez, G.; Wang, J. C.-Y.,; Zlotnick, A. A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation. 2024.
Title:
Raw data for "A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation"
Spectroscopy data were collected on a BioTek Synergy H1 plate reader, then exported to and analyzed in Excel. 3D charts used in the manuscript were generated with OriginPro. Microscopy images are in proprietary .nd2 format of Nikon Elements software. .nd2 files were opened and processed with ImageJ. Gels were imaged on a BioRad Chemidoc and labeled and saved in .ai files.
Laughlin, P. M.; Young, K.; Gonzalez-Guiterrez, G.; Wang, J. C.-Y.,; Zlotnick, A. A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation. 2024.
Title:
Raw data for "A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation"
Spectroscopy data were collected on a BioTek Synergy H1 plate reader, then exported to and analyzed in Excel. 3D charts used in the manuscript were generated with OriginPro. Microscopy images are in proprietary .nd2 format of Nikon Elements software. .nd2 files were opened and processed with ImageJ. Gels were imaged on a BioRad Chemidoc and labeled and saved in .ai files.
Laughlin, P. M.; Young, K.; Gonzalez-Guiterrez, G.; Wang, J. C.-Y.,; Zlotnick, A. A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation. 2024.
Title:
Raw data for "A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation"
Spectroscopy data were collected on a BioTek Synergy H1 plate reader, then exported to and analyzed in Excel. 3D charts used in the manuscript were generated with OriginPro. Microscopy images are in proprietary .nd2 format of Nikon Elements software. .nd2 files were opened and processed with ImageJ. Gels were imaged on a BioRad Chemidoc and labeled and saved in .ai files.
Laughlin, P. M.; Young, K.; Gonzalez-Guiterrez, G.; Wang, J. C.-Y.,; Zlotnick, A. A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation. 2024.
Title:
Raw data for "A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation"
Spectroscopy data were collected on a BioTek Synergy H1 plate reader, then exported to and analyzed in Excel. 3D charts used in the manuscript were generated with OriginPro. Microscopy images are in proprietary .nd2 format of Nikon Elements software. .nd2 files were opened and processed with ImageJ. Gels were imaged on a BioRad Chemidoc.
Laughlin, P. M.; Young, K.; Gonzalez-Guiterrez, G.; Wang, J. C.-Y.,; Zlotnick, A. A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation. 2024.
Title:
Raw data for "A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation"
Soil geochemical analysis was performed using samples from around the US. The sampling and analysis protocols differ by data source (this is available at www.mapmyenvironment.com). The data in this table is soil lead concentration in parts per million binned by municipality in which it was collected.
Rare Earth Elements (REE) phosphates (monazite, xenotime, and rhabdophane) are critical REE-bearing minerals typically formed in hydrothermal and magmatic ore deposits. The ther-modynamic properties of those REE minerals are crucial to understanding the solubility, speciation, and transport of REE complexes. However, the reported standard state Gibbs free energy of for-mation (∆Gof) for these minerals in the literature vary up to 25 kJ mol−1. Here, we present linear free energy relationships that allow the evaluation and estimation of the ∆Gof values at 25 °C and 1 bar for the three minerals from the ionic radius (rREE3+) and the non-solvation Gibbs energy contribution to the REE3+ aqua ion (∆Gon, REE3+): ∆Gof, monazite – 399.71 rREE3+ = 1.0059 ∆Gon, REE3+ – 2522.51; ∆Gof, xenotime – 344.08 rREE3+ = 0.9909 ∆Gon, REE3+ – 2451.53; ∆Gof, rhabdophane – 416.17 rREE3+ = 1.0067 ∆Gon, REE3+ – 2688.86. Moreover, based on the new dataset derived for REE end-members, we re-fitted the binary Margules parameter (W) from previous theoretical calculations into linear correlations: W + 0.00204 ∆Go'n, monazite = 39.3549 ∆V + 0.0641; W + 0.00255 ∆Go'n, xenotime = 25.4885 ∆V – 0.0062. The internally con-sistent thermodynamic properties of these REE phosphates are incorporated into the computer program SUPCRTBL, which is freely available at the site https://models.earth.indiana.edu.
Citation to related publication:
Title:
Recommended standard thermodynamic dataset of monazite, xenotime, and rhabdophane
Rare Earth Elements (REE) are critical minerals (metals) for the transition from fossil fuels to renewable and clean energy. Accurate thermodynamic properties of REE minerals and other crystalline solids are crucial for geochemical modeling of the solubility, speciation, and transport of REE in ore formation, extraction, chemical processing, and recycling processes. However, the Gibbs free energies of formation (∆Gof, REEX) for these solids from different sources vary by 10s kJ/mol. We applied the Sverjensky linear free energy relationship (LFER) to evaluate their internal consistency and predict the unavailable ∆Gof of the REE solids. By considering both the effects of ionic radius size and corresponding aqueous ion properties, the Sverjensky LFER,
allows estimates with much accuracy and precision. Here, rREEZ+ represents the Shannon-Prewitt ionic radii (Å) of REEZ+, and ∆Gon, REEZ+ denotes the non-solvation contribution to the ∆Gof of the aqueous REEZ+ ion. X represents the remainder of the compounds. In this study, the parameters aREEX, bREEX, and βREEX were regressed from ∆Gof compilations in the literature for 13 isostructural families. Based on these linear relationships, we recommend a set of internally consistent ∆Gof, REEX for 119 end-members of REE oxides, hydroxides, chlorides, fluorides, carbonates, hydrous carbonates, and ferrites. These ∆Gof, REEX are combined with experimental or predicted values of So, Vo, and Cpo from the literature and incorporated into a new SUPCRT database, which allows the calculations of thermodynamic properties to high P-T conditions (e.g., up to 1000 oC and 5 kb). The log Ksp of REE solid dissociation reactions were incorporated into a modified USGS program PHREEQC for calculations of speciation, solubility, and reactive transport. These thermodynamic databases will also be incorporated into the MINES database to be used together with the GEMS code package in the future.
Citation to related publication:
Title:
Linear correlations of Gibbs free energy for rare earth element oxide, hydroxide, chloride, fluoride, carbonate, and ferrite minerals and crystalline solids
We recommend a set of internally consistent ΔGof, REEX for 119 end-members of REE oxides, hydroxides, chlorides, fluorides, carbonates, hydrous carbonates, and ferrites. These ΔGof, REEX are combined with experimental or predicted values of So, Vo, and Cpo from the literature and incorporated into a new SUPCRT database, which allows the calculations of thermodynamic properties to high P-T conditions (e.g., up to 1000 oC and 5 kb). The log Ksp of REE solid dissociation reactions were incorporated into a modified USGS program PHREEQC for calculations of speciation, solubility, and reactive transport. These thermodynamic databases will also be incorporated into the MINES database to be used together with the GEMS code package in the future.
Citation to related publication:
Title:
Linear correlations of Gibbs free energy for rare earth element oxide, hydroxide, chloride, fluoride, carbonate, and ferrite minerals and crystalline solids
Sanborn Fire Insurance Maps were made for the interests of fire insurance companies, but because they are detailed, building-by-building depictions of most urban areas, they are useful for many kinds of research.
